Stent intervention is an effective treatment for vascular stenosis. At present, the stents used clinically are mainly permanent stents, which are mainly characterized by long-term dual antibody, late thrombosis, fatigue fracture of stents, and difficulty in secondary intervention. Besides, artifacts produced by metals can affect magnetic resonance (MRI) angiography and computed tomography (CT) angiography. The ideal stent should provide sufficient mechanical support to the lesion site and be gradually absorbed by the body after the vascular healing. Bioabsorbable scaffolds were developed based on this concept.
Bioabsorbable scaffolds are made of biodegradable/corrosive materials with the purpose of "disappearing after completion of the task". After implantation in the patient, they can initially support the diseased blood vessels and prevent the negative remodeling of the diseased blood vessels. With the improvement of the peripheral environment of the diseased vessels and the completion of the remodeling of the vascular structure, the scaffolds in the vessel gradually degrade/corrode and are absorbed. Compared with permanent stents, the advantages of absorbable scaffolds can be summarized as follows:
(1) short-term reduction of vascular elastic retraction and acute occlusion to prevention restenosis;
(2) long-term can reduce stent thrombosis and shorten the time of antiplatelet treatment;
(3) eliminate the artifacts of CT and MRI and other imaging examinations during the follow-up;
(4) can be used in the same place to intervene for many times.